NFL Week 5 Overreactions
USAT’s Lorenzo Reyes breaks down the best games from NFL Week 5.
Sports Seriously
The New England Patriots and New Orleans Saints play on Oct. 12, at the Saints’ Caesars Superdome in a game on the NFL Week 6 schedule.
Which team will win the NFL Week 6 game?
Check out these NFL Week 6 picks and NFL Week 6 predictions for the game, which can be seen at 10 a.m. MST on CBS (stream with FUBO).
The Patriots are a 3.5-point favorite over the Saints in NFL Week 6 odds for the game, courtesy of BetMGM Sportsbook.
New England is -190 on the moneyline, while New Orleans is +155. The over/under (point total) is set at 46 points.
NFL Week 6 picks: Eagles at Giants | Broncos vs Jets | Rams at Ravens | Cowboys at Panthers | Cardinals at Colts | Seahawks at Jaguars | Chargers at Dolphins | Browns at Steelers | Patriots at Saints | Titans at Raiders | 49ers at Buccaneers | Bengals at Packers | Lions at Chiefs | Bills at Falcons | Bears at Commanders | The Republic’s score predictions
Watch Patriots at Saints live on FUBO (free trial)
Jeremy Cluff writes: “Drake Maye and the Patriots have won two straight, including an impressive win over the Buffalo Bills in NFL Week 5. Can Spencer Rattler and the Saints upset New England? Not if Maye continues to play mistake-free football (22-for-30, 273 yards vs. Bills).”
Bookies.com: Bet the Patriots to cover vs Saints
Bill Speros writes: “Drake Maye could hit 300 passing yards for the first time in his career this week inside Caesars Superdome against the ‘Aints. Both teams scored upset wins on Sunday. But New England’s victory over the Bills in Orchard Park was the most-substantial win for the franchise since Super Bowl 53.”
The site’s formula predicts that the Patriots will win the NFL Week 6 game against the Saints.
ESPN: Patriots have a 60.4% chance to beat Saints on Sunday
The site gives the Saints a 39.3% shot at winning the NFL Week 6 game, with the remaining percentage accounting for a tie.
Dimers: Patriots 23, Saints 20
It writes: “After extensive simulations, our model gives the Patriots a win probability of 63%, while the Saints have a win probability of 37%.”
Sportsnaut: New England Patriots 27, New Orleans Saints 17
Matt Johnson writes: “The New England Patriots defense alone should help them avoid falling into the same trap that New York did against the New Orleans Saints. New England’s secondary is now healthy and should be able to limit Chris Olave and Rashid Shaheed, even if this young Saints’ offensive line holds up fairly well in pass protection. While it will be a competitive game, the Patriots’ defense and the play-making ability of quarterback Drake Maye, with the help of a true go-to receiver in Stefon Diggs, should propel New England to the victory.”
NFL’s highest paid players in 2025: Quarterbacks | Running backs | Wide receivers | Tight ends | Offensive linemen | D-linemen | Cornerbacks | Safeties | Linebackers | Edge rushers | Highest paid NFL players: Overall | By position | By team
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
Support local journalism: Subscribe to azcentral.com today. Sign up for azcentral Preps Now. And be sure to subscribe to our daily sports newsletters so you don’t miss a thing.
